Genét Finnegan PA-C consulting with a patient interested in Restylane Refyne/Defyne dermal filler in NY, NY

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Restylane® Refyne/Defyne

Over time, lines and creases start to form around the nose and mouth. Restylane Refyne and Defyne are injectable treatments designed to target those lines for a more youthful appearance.

  • Downtime: VERY MINIMAL
  • Pain Level: Very Minimal
  • Results Duration: 9-12 months


Loss of volume, nasolabial folds, marionette lines, and smile lines

Side Effects:

Slight redness or swelling immediately following treatment


Primarily used around the nose and mouth

Follow Up:

None required

How Performed:

Filler is injected to the desired areas using tiny needles


Topical anesthesic available

Procedure Type:


Expected Outcome:

Reduced facial lines and restored volume


Results visible immediately

patient receiving Restylane® Refyne and Defyne dermal filler injections from a NYC dermatologist

Fight back against aging skin and explore a wide range of treatment and procedure options to reduce wrinkles, lines, and creases, including Restylane® Refyne and Defyne. These products leverage hyaluronic acid for subtle and natural-looking results.

Spring St. Dermatology in NYC offers individualized patient care and a comprehensive medical and cosmetic dermatology center that serves Soho and Uptown. Our medical spa’s board-certified dermatologists aim to achieve natural and effective results with customized, minimally-invasive cosmetic treatment options.

What is Restylane Refyne/Defyne?

Restylane Refyne and Defyne are FDA-approved dermal fillers that use hyaluronic acid to reduce the appearance of smile lines and nasolabial folds.

With aging comes more noticeable wrinkles and lines that can be targeted with Refyne and Defyne. They are flexible fillers, making them more effective at eliminating lines around the mouth without compromising your ability to make natural facial expressions.

Restylane Refyne and Defyne are designed to treat facial wrinkles using XpressHAn technology, which creates a more natural feel. Refyne is mainly used for mild to moderate nasolabial folds and facial lines, while Defyne offers additional correction for more severe wrinkles.

What do Restylane Refyne/Defyne treat?

Refyne and Defyne are versatile fillers that can be used on a wide variety of treatment areas. They are primarily used to treat:

    • Smile lines: Small vertical lines that appear at the corners of the mouth
    • Nasolabial folds: Lines that extend from the nose to the corner of the mouth
    • Marionette lines: Creases that extended from the corner of the mouth to the chin

Who is a candidate for a Restylane Refyne/Defyne treatment?

Restylane Refyne and Defyne are recommended for patients with mild to severe lines and creases. Depending on your unique needs and the severity of your lines and folds, we may recommend one over the other.

Restylane Refyne and Defyne are effective on all skin types and tones.

What to Expect During a Treatment Session

Treatment sessions at our medical spa for Restylane Refyne and Defyne can be completed in 5-30 minutes. The chosen filler is injected into the target area with a fine needle.

Most patients find the treatment to be quick and relatively comfortable.

Benefits of Restylane Refyne/Defyne

Quick procedure

No downtime required

Smooth away facial lines

Minimize deeper creases

Restore skin’s youthful appearance

Create natural improvement

Schedule your Restylane Refyne/Defyne Treatment at our NYC Medical Spa

Spring St. Dermatology can help you begin your journey to achieve cosmetic beauty. Our dermatologists emphasize natural-looking and youthful skin by identifying the correct treatments for each patient. Your dermatologist can help you choose the right treatments to achieve your goals and desired look.

Find out if Restylane Refyne or Defyne is suitable for you. Contact us to schedule a consultation and learn more about how we can help eliminate lines and creases with Restylane Refyne and Defyne.

Restylane Contour Questions & Answers

Q: What side effects are associated with Restylane Refyne/Defyne?

A: Restyland Refyne and Defyne, like many other dermal fillers, can cause redness and minor swelling in some patients. Any side effects should subside within a few days.

Restylane Refyne and Defyne are FDA-approved dermal fillers that, when correctly handled, are safe and effective. Our board-certified dermatologists are highly trained and experienced with dermal fillers, ensuring the best possible experience and results for our patients.

Q: When will I see results?

A: Some of our patients will see some initial improvement as soon as they leave our office. Those results can continue to improve for a week or two as minor swelling subsides and the filler evens out in the treatment areas.

Q: How long will my results last?

A: Results are shown to last for up to 12 months, although actual time can vary from patient to patient. You can maintain your desired appearance with regularly scheduled treatment sessions at either our Soho or Uptown locations.

Q: Does a Restylane Refyne/Defyne treatment hurt?

A: Restylane Refyne and Defyne are minimally-invasive treatments and do not involve a local anesthetic. Many patients find the treatment to be quick and comfortable without severe pain.

If you are concerned about pain management, talk to your Spring St. dermatologist about a topical numbing cream before your procedure.

Q: Is there any recovery after my Restylane Refyne/Defyne treatment?

A: Restylane Refyne and Defyne treatments require little to no downtime because they are minimally-invasive procedures. Patients can return to regular daily activities immediately after treatment.

Any swelling or redness will not be overly noticeable and should resolve within one to two days.

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75 Spring Street, Floor 2
New York, NY 10012
Monday - Friday: 8:00 am - 7:00 pm
Saturdays: 10:00 am - 4:00 pm

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4 West 58th Street, 13th Floor
New York, NY 10019

Monday - Friday: 8am6pm

Same-Day Appointments Now Available

Title Address Description
75 Spring Street, Floor 2 New York, NY 10012

75 Spring Street, Floor 2
New York, NY 10012

Monday – Friday: 9am – 8pm

4 West 58th street, 13th Floor New York, NY 10019

4 West 58th street, 13th Floor

New York, NY 10019

Sun & Sat: 10am-3pm

Mon-Fri: 8am-6pm

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